Sarcoma formation is thought to be related to adjuvanted vaccines because they trigger a more significant inflammatory response.
Administering vaccines at the recommended sites assists in identifying the likely causative agent for local reactions and
neoplasia and aids in management after a sarcoma has formed. The recommendation to administer vaccines in the distal limbs
of cats has reduced the presence of sarcomas in the scapular area. However, an unintended result of this vaccination site
change has been an increase in sarcomas in the flank area. When a cat crouches during vaccine administration, the cat's skin
is loose, and the vaccine may inadvertently be given in the lateral abdomen instead of the limb. Unfortunately, the flank
area is not conducive for sarcoma management. This indicates a need for increased precision during vaccination. Team members
can be especially helpful in this regard by using the appropriate minimal effective restraint.
For more on vaccine administration and patient care during vaccination, see Tips for safe vaccine administration and patient care.